心理行为干预与多奈哌齐治疗血管性痴呆的认知康复研究

目的探讨心理行为干预对血管性痴呆(VD)患者的认知康复效果。方法将56例轻、中度VD简易智力状态量表(MMSE)8～22分]患者随机分为研究组23例,对照组23例,进行为期6个月临床治疗观察。结果研究组与对照组MMSE、日常生活自理量表(ADL)评分在治疗后3个月和6个月均下降,但研究组评分下降显著(P<0.01)。结论在小剂量药物治疗的基础上,持续有计划地对轻、中度VD患者进行心理行为干预训练,患者的认知功能和日常生活自理能力改善更加明显,而药物不良反应较轻。此训练经济、方便,患者及家属容易接受和坚持。

Control study of cognitive rehabilitation treatment in vascular dementia patients between psychological behavior intervention methods and donepezil

ObjectiveTo explore the cognitive rehabilitation effect of psychological behavior intervention treatment in vascular dementia(VD) patients. MethodsThe 56 light to moderate cases with VD simple mental status scale(MMSE) 8~22 points] were randomly divided into the research group and the control group,each group have 23 cases.All patients accepted 6 month treatment.ResultsThe MMSE,daily life self-care scale(ADL) scores 3 months and after 6 months treatment of the research group was more obviously decreased than that of the control group(P<0.01).ConclusionCombine small doses of drugs and behavior intervention training in light to moderate VD patients continued in a planned way,the patients’ cognitive functions and daily self-care skill improve more evident,and their adverse drug reactions are lighter.And the behavior intervention training is economic,convenient,and is easy to accepted and persistence by the patient and their family.