| 乙醇对雄性小鼠精子生成的影响 |
| |
| 引用本文： | 马明月,张玉敏,李海山,崔金山. 乙醇对雄性小鼠精子生成的影响[J]. 工业卫生与职业病, 2000, 26(4): 209-212 |
| |
| 作者姓名： | 马明月 张玉敏 李海山 崔金山 |
| |
| 作者单位： | 1. 中国医科大学环境卫生学教研室,沈阳市,110001
2. 沈阳医学院毒理学教研室 |
| |
| 摘 要： | 分析经口染毒乙醇３５天的雄性小鼠的精子数量、活动度、精子畸形率及睾丸细胞染色体畸变，研究乙醇对雄性小鼠精子生成的影响。结果表明，４０００ｍｇ／ｋｇ组和４５００ｍｇ／ｋｇ组小鼠精子活动度明显下降；３０００，４０００和４５００ｍｇ／ｋｇ组精子畸形率明显增高；４５００ｍｇ／ｋｇ组睾丸细胞染色体畸变率明显增高，与阴性对照组相比，上述指标差异均有显著性（Ｐ〈０．０１）。说明乙醇对小鼠的精子生成有一定损害作用
|
| 关 键 词： | 乙醇 精子生成 睾丸细胞 染色体畸变 |
Effect of Ethanol on the Spermatogenesis of Male Mice |
| |
| Ma Mingyue et al. Effect of Ethanol on the Spermatogenesis of Male Mice[J]. Industrial Health and Occupational Diseases, 2000, 26(4): 209-212 |
| |
| Authors: | Ma Mingyue et al |
| |
| Abstract: | After gavaged with ethanol for 35 days,the number,motility and deformity of sperm and chromosome aberration in testicle cells of male mice were determined.The results showed that in 4 000 mg/kg group the sperm motility decreased,in 3 000 mg/kg and 4 000 mg/kg groups the rate of sperm deformity increased,and in 4 500 mg/kg group the rate of chromosome aberration in testicle cells increased.It indicated that ethanol could damage spermatogenesis in mice. |
| |
| Keywords: | Ethanol Spermatogenesis Testicle cell Chromosome aberration |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
