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女贞子体外抗氧化活性研究
引用本文:刘新,夏雪奎,袁文鹏,张永刚,刘昌衡,王长云. 女贞子体外抗氧化活性研究[J]. 山东中医学院学报, 2010, 0(4): 364-365
作者姓名:刘新  夏雪奎  袁文鹏  张永刚  刘昌衡  王长云
作者单位:[1]山东省科学院生物研究所/山东省生物传感器重点实验室,山东济南250014 [2]山东省科学院中日友好生物技术研究中心,山东省应用微生物重点实验室,山东济南250014 [3]中国海洋大学医药学院,海洋药物教育部重点实验室,山东青岛266003
基金项目:国家自然科学基金(编号:30572314); 山东省优秀中青年科学家科研奖励基金(编号:03BS109)
摘    要:目的:研究女贞子的体外抗氧化活性。方法:在体外化学模拟的条件下,采用比色法测定了女贞子提取物对二苯代苦味酰基(DPPH)自由基和羟基自由基的清除能力,抗脂质过氧化能力,还原能力以及总体抗氧化能力。结果:女贞子醇提物对DPPH自由基和羟基自由基显示出较强的清除能力,具有一定的抗脂质过氧化能力和还原能力,其总体抗氧化能力也较强。结论:女贞子具有较强的抗氧化活性,可以作为潜在的天然抗氧化剂开发利用。

关 键 词:女贞子  抗氧化  自由基  比色法

Study on antioxidative activities of Ligustrum lucidum Ait.in vitro
LIU Xin,XIA Xue-kui,YUAN Wen-peng,ZHANG Yong-gang,LIU Chang-heng,WANG Chang-yun. Study on antioxidative activities of Ligustrum lucidum Ait.in vitro[J]. , 2010, 0(4): 364-365
Authors:LIU Xin  XIA Xue-kui  YUAN Wen-peng  ZHANG Yong-gang  LIU Chang-heng  WANG Chang-yun
Affiliation:1.Biology Institute of Shandong Academy of Sciences/Key Laboratory for Biosensors of Shandong Province,Jinan 250014,China;2.Biotechnology Center of Shandong Academy of Sciences/Key Laboratory for Applied Microbiology of Shandong Province,Jinan 250014,China;3.Key Laboratory of Marine Drugs of Ministry of Education,Faculty of Medicine and Pharmacy of Ocean University of China,Qingdao 266003,China)
Abstract:Objective:To study the antioxidant activities of Ligustrum lucidum Ait.in vitro.Methods:The antioxidant properties of different extracts of Ligustrum lucidum Ait.were evaluated by different antioxidant tests,including DPPH free radical scavenging activity,hydroxyl radical scavenging activity,preventing effect on lipid peroxidation,reducing power and assay of total antioxidant activity in vitro chemical simulated systems with colorimetry method.Results:The ethanol extract of Ligustrum lucidum Ait.exhibited notable scavenging effect to DPPH free radical and hydroxyl radical,had some functions of inhibiting lipid peroxidation and reducing power,and the total antioxidant activity was relatively strong.Conclusion:Ligustrum lucidum A.showed antioxidant activity and could be applied as a potential natural antioxidant.
Keywords:Ligustrum lucidum Ait.  antioxidant  free radical  colorimetry
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