骨关节病中医证型分布及演变规律的研究

目的探讨骨关节病中医证型分布及演变规律。方法对275例骨性关节炎患者的证型分布进行临床流行病学研究,运用单因素ANOVA、非参数Kruskal-Wallis秩和检验及Pearson Chi-Square统计方法调查骨关节病不同性别、民族、年龄、病程及X线片方面的证型分布及演变规律。结果本病主要证型为风寒湿痹、湿热蕴结、肝肾亏虚、痰瘀互结,其中以肝肾亏虚型为主,约占36.4%。女性患者居多,为男性的1.7倍。肝肾亏虚型、痰瘀互结型患者随着年龄及病程的延长,其发生率呈上升趋势。风寒湿痹型患者随着病程的延长,其发生率呈下降趋势。湿热蕴结型的变化无统计意义。结论骨性关节炎患者多见于女性,病变初期以风寒湿痹型为主,后期以肝肾亏虚型为主。湿热蕴结型是骨性关节炎病程发展中的一个常见证,针对各期辨证施治,有利于提高防治慢性并发症的临床效果。

Study on the rule of distribution development of the Chinese medicine syndromes of osteoarthritis

Objective It is to study the rule of distribution and development of the Chinese medicine syndromes of osteoarthritis.Methods Clinical epidemiology research on syndrome distribution was carried on in 275 patients with osteoarthritis.The rules of syndrome distribution and development in different sex,race,age,course of illness and X slice of the patients were investigated by single factor ANOVA,non-parameter Kruskal-Wallis and the Pearson Chi-Square statistics method.Results The main syndromes of psoriasis were the cold wet,the hot and damp,the liver and kidney shortage,and the phlegm and stagnant blood knot with each other,and the liver and kidney shortage that about 36.4% could be most commonly seen.The female patients were 1.7 times more than the male.There was a rising trend of occurrence rate of the liver and kidney shortage and the phlegm and stagnant blood knot with each other along with the extension of the age and the course of illness,however,the rate of the cold wet was down trend.The varieties of the hot and damp didn't show any statistics meaning.Conclusion Osteoarthritis sufferer is mostly seen in female.The pathological change in the early stage mainly is the cold wet,the liver and kidney shortage is seen at the end of the stage.The hot and damp is an often witness in the course of osteoarthritis development,we can aim at diagnosing of each period,be advantageous to the clinical result that the exaltation prevents and cure chronic complications.