富硒蛋白对小鼠免疫功能影响

目的观察富硒蛋白对正常小鼠免疫功能的影响作用。方法选用48只继康的ICR小鼠，随机分成4组，在饲料中分别加入贫硒蛋白、贫硒蛋白与亚硒酸钠混合物、富硒牛奶、富硒蛋白，进行30d的喂饲后测定小鼠淋巴器官指数、迟发型变态反应、溶血空斑形成数。结果富硒蛋白能够促进小鼠溶血空斑的形成，刺激迟发型变态反应，作用优于相同硒含量的富硒牛奶或者贫硒蛋白与无机硒的混合饲料（P〈0．05）。结论该富硒蛋白产品有提高小鼠体液免疫、细胞免疫功能的作用。

Effect of selenium- enriched protein on immune function of mice

Objective To study the influence of selenium-enriched proteins,which were made from selenium-enriched milk,on the immune function of the health mice.Methods Forty-eight healthy mice were chosen and randomly divided into 4 groups:normal milk group,normal milk+inorganic selenium(Na_2SeO_3) group,selenium-enriched milk group,selenium-enriched protein group.30days later,the index of lymphoid organ of mice,delayed-type hypersensitivity(DTH),the number of plague forming cell were determined,respectively.Results The selenium-enriched protein could increase the number of plague forming cell(PFC),and stimulated DTH.Its influence on the immune of the mice was stronger than those form normal milk+inorganic selenium group and selenium-enriched milk group under the same dosage.Conclusion The selenium-enriched protein can improve cellular immunity and humoral immunity of mice.