| 正交试验优选通脉颗粒中葛根素的提取工艺 |
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| 引用本文： | 余建清,柳惠斌,雷嘉川.正交试验优选通脉颗粒中葛根素的提取工艺[J].中国中医药信息杂志,2005,12(12):54-55. |
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| 作者姓名： | 余建清 柳惠斌 雷嘉川 |
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| 作者单位： | 1. 武汉大学人民医院药学部,湖北,武汉,430060
2. 武汉大学药学院,湖北,武汉,430072 |
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| 摘 要： | 目的优选通脉颗粒中葛根素的提取工艺。方法采用正交试验法,考察乙醇浓度、乙醇用量、提取时间及提取次数对提取率的影响。结果所考察因素中,对葛根素提取率的影响程度为:乙醇浓度>提取次数>乙醇用量>提取时间。结论最佳提取条件为:80%乙醇12倍量,回流提取3次,每次3h。
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| 关 键 词： | 通脉颗粒 葛根素 正交试验 |
| 文章编号： | 1005-5304（2005）12-0054-02 |
| 收稿时间： | 2005-02-04 |
| 修稿时间： | 2005年2月4日 |
Study on Extraction Technics of Puerarin from Tongmai Granule by the Method of Orthogonal-test Optimization |
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| YU Jian-qing,LIU Hui-bin,LEI Jia-chuan.Study on Extraction Technics of Puerarin from Tongmai Granule by the Method of Orthogonal-test Optimization[J].Chinese Journal of Information on Traditional Chinese Medicine,2005,12(12):54-55. |
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| Authors: | YU Jian-qing LIU Hui-bin LEI Jia-chuan |
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| Institution: | 1.Department of Pharmacy, Renmin Hospital of Wuhan University, Wuhan 430060, China; 2. College of Pharmacy, Wuhan University, Wuhan 430072, China |
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| Abstract: | Objective To optimize the extraction technics of puerarin from Tongmai Granule.Methods The extraction rate of puerarin optimized condition(ethanol concentration,extraction time,solvent quantity and extraction times)was determined by orthogonal design.Results The order of factors to affect the puerarin extraction was ethanol concentration>extraction times> solvent quantity>extraction time.Conclusion The optimum extraction was described as follows :The concentration of alcohol was 80%,volume of alcohol was 12 times raw herb,and the herb was extracted 3 times with 3 h for each time. |
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| Keywords: | Tongmai Granule puerarin orthogonal test |
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