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一氧化碳对脂质代谢、脂质过氧化影响的研究
引用本文:涂荔卿,胡迪生.一氧化碳对脂质代谢、脂质过氧化影响的研究[J].福建医科大学学报,1992(2).
作者姓名:涂荔卿  胡迪生
作者单位:福建医学院劳动卫生学教研室,浙江医科大学预防医学系
摘    要:通过动物实验和流行病学调查,探讨低浓度CO对脂质代谢及脂质过氧化影响。结果表明CO引起脂质代谢紊乱,增高动脉粥样硬化的危险性;CO导致脂质过氧化,血清LPO增高,可能是引发动脉粥样硬化早期改变的重要因素之一。

关 键 词:一氧化碳  脂质代谢  脂质过氧化  动脉粥样硬化

Effects of Carbon Monoxide on Lipid Metabolism and Lipid Peroxidation
Tu Liqing,Hu Disheng Departmint of Industrial Medicine and Occupational Disease,Fujian Medical College,Fuzhou Faculty of Preventive Weicine,Zhejiang Medical College,Hangzhou.Effects of Carbon Monoxide on Lipid Metabolism and Lipid Peroxidation[J].Journal of Fujian Medical University,1992(2).
Authors:Tu Liqing  Hu Disheng Departmint of Industrial Medicine and Occupational Disease  Fujian Medical College  Fuzhou Faculty of Preventive Weicine  Zhejiang Medical College  Hangzhou
Abstract:An animal experiment and epidemiological investigation in workers exposed to CO in a chemical fertilizer factory were carried out, to find out the effects of low concentration CO on lipid metabolism and lipid peroxidation. Results showed: CO changed the lipid metabolism, increased the risk of atheroselerosis. Exposing to CO induced lipid peroxidation, and serum LPO increased. Lipid peroxidation injuries induced by CO might be one of the important factors of inducing pathologic changes in early pe- riod of atherosisclerosis.
Keywords:carbon monoxide  lipid metabolism  lipid peroxidation  atherosclerosis
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