| 用体感诱发电位来评价纳洛酮治疗大面积脑梗死疗效的研究 |
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| 引用本文： | 李剑鹏,童绥君. 用体感诱发电位来评价纳洛酮治疗大面积脑梗死疗效的研究[J]. 福建医药杂志, 2005, 27(3): 22-24 |
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| 作者姓名： | 李剑鹏 童绥君 |
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| 作者单位： | 1. 福建医科大学2002级研究生
2. 福建医科大学附属厦门市第一医院神经内科,361000 |
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| 摘 要： | 目的应用体感诱发电位的脑功能评价法观察纳洛酮治疗急性大面积脑梗死的即刻疗效。方法选择急性大脑中动脉供血区大面积脑梗死的患者28例，给予纳洛酮0．8mg肌注，观察指标为肌注前后SEP的N20、CCT。结果治疗后患侧N20波幅出现或增高，而CCT较治疗前无明显变化。结论纳洛酮治疗大面积脑梗死有确定的即刻疗效，提高了梗死侧大脑皮层兴奋性，但无助于改善脑梗死后的神经传导功能。
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| 关 键 词： | 脑梗死 纳络酮 体感诱发电位 药物治疗 神经纤维 |
| 文章编号： | 1002-2600(2005)03-0022-03 |
The study to evaluate the naloxone''''s effect for large brain infarction with somatosensory evoked potentials |
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| Li Jianpeng,TONG Suijun. The study to evaluate the naloxone''''s effect for large brain infarction with somatosensory evoked potentials[J]. Fujian Medical Journal, 2005, 27(3): 22-24 |
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| Authors: | Li Jianpeng TONG Suijun |
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| Affiliation: | Li Jianpeng,Tong Suijun.Department of Neurology,Xiamen First Hospital Affileted to Fujian Medical University,Xiamen 361000,China |
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| Abstract: | Objectvie To evaluate the instant effect of naloxone for large brain infarction with somatosensory evoked potentials (SEP).Methods In twenty-eight patients of acute cerebral infarction,naloxone 0.8 mg was administered im,st.Then the different amplitudes of N_ 20 and CCT of SEP before and after treatment were analysed.Results The N_ 20 amplitudes or recurrence were found in the patients.But the CCT had no variety after the treatment.Conclusion In short time,naloxone is beneficial to the large cerebral infarction patients,and it can increase the cerebral cortical excitability of the infarction.At the same time,naloxone can not ameliorate nervous conductivity. |
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| Keywords: | Cerebral infarction Naloxone Somatosensory evoked potentials |
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