| 钙敏感受体在动脉粥样硬化中的作用研究进展 |
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| 引用本文： | 商瑀家,李玉霞,宋佳新,李宏霞.钙敏感受体在动脉粥样硬化中的作用研究进展[J].基础医学与临床,2020,40(3):395-398. |
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| 作者姓名： | 商瑀家 李玉霞 宋佳新 李宏霞 |
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| 作者单位： | 哈尔滨医科大学 基础医学院 病理生理学教研室,黑龙江 哈尔滨,150086 |
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| 摘 要： | 钙敏感受体(CaSR)是G蛋白偶联受体C家族的成员之一,广泛表达于体内不同组织细胞,参与机体多种病理生理过程。CaSR能够通过调控血管内皮细胞损伤、炎性反应、血管平滑肌细胞增殖和迁移及血管钙化过程,参与动脉粥样硬化的发生发展。
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| 关 键 词： | 钙敏感受体 动脉粥样硬化 血管平滑肌细胞 |
Research progress on the role of calcium sensing receptor in atherosclerosis |
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| SHANG Yu-jia,LI Yu-xia,SONG Jia-xin,LI Hong-xia.Research progress on the role of calcium sensing receptor in atherosclerosis[J].Basic Medical Sciences and Clinics,2020,40(3):395-398. |
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| Authors: | SHANG Yu-jia LI Yu-xia SONG Jia-xin LI Hong-xia |
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| Institution: | (Department of Pathophysiology,School of Basic Medicine,Harbin Medical University,Harbin 150086,China) |
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| Abstract: | Calcium sensing receptor(CaSR)is a member of the G protein-coupled receptor C family.It is widely expressed in different tissue cells in the body and functions in various pathophysiological processes of the body.CaSR can participate in the development of atherosclerosis by regulating vascular endothelial cell injury,inflammatory response,proliferation and migration of vascular smooth muscle cells and vascular calcification. |
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| Keywords: | calcium sensing receptor atherosclerosis vascular smooth muscle cells |
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