门诊流动人口性病就诊者支原体检测及耐药情况分析

目的了解性病门诊外来流动人口患者支原体感染及耐药情况。方法对1200例性病门诊患者进行了支原体培养鉴定及抗菌药物敏感性试验。结果支原体Uu和（或）Mh阳性总检出率为49．3％（592／1200），其中单纯Uu阳性率82．6％（489／592），单纯Mh阳性5．9％（35／592），Uu＋Mh混合感染11．5％（68／592）。男性感染率为34．5％（204／592），女性感染率为65．5％（388／592），女性支原体感染率高于男性（P〈0．05）。耐药性最高的分别为环丙沙星（72．3％）、氧氟沙星（66．0％）、壮观霉素（31．6％），敏感性最高的分别为强力霉素（89．2％）、交沙霉素（83．8％）、罗红霉素（81．3％）、美满霉素（76．4％）和克拉霉素（76．4％）。结论支原体感染依然是外来流动人口非淋菌性尿道（宫颈）炎主要的病因，监测支原体的耐药性对指导临床合理使用抗生素具有重要意义。

Infection status and antimicrobial resistance of mycoplasma in STD patients in fluid population

Objective To realize infection status and antibiotic resistance of mycoplasma from patients in fluid population in order to apply correct treatment in STD.Methods 1200 patients were chosen to test ureaplasma urealyticum(UU),mycoplasma hominis(MH)and Uu Mh at STD clinic,at the same time the drug sensitivity was analyzed.Results The total infection rates were 49.3%(592/1200).The infection rates of UU,MH and UU MH were 82.6%(489/592),5.9%(35/592),and 11.5%(68/592)respectively.The infection rate in female was 65.5%,higher than that(34.5%)in male(P<0.05).72.3% of Uu and/or Mh were resistant to ciprofloxacin.66.0% of them were resistant to ofloxacin.31.6% of them were resistant to actinospectacin.Listing the drug sensitivity from high to low was deoxycycline(89.2%),josamycin(83.8%),roxithromycin(81.3%),minocycline(76.4%),Clarithromycin(76.4%).Conclusions The mycoplasma infection is still the main causative agent of nongonococcal urethritis(cervicitis).The surveillance study on mycoplasma resistance is very important.