| 豚鼠脑干听觉中枢及内侧膝状体P物质受体阳性产物的分布 |
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| 引用本文： | 邱建华,王锦玲.豚鼠脑干听觉中枢及内侧膝状体P物质受体阳性产物的分布[J].第四军医大学学报,1997,18(1):9-12. |
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| 作者姓名： | 邱建华 王锦玲 |
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| 作者单位： | 第四军医大学西京医院耳鼻咽喉科!西安710033(邱建华，王锦玲，刘顺利)，第四军医大学解剖学教研室(施际武，李云庆) |
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| 基金项目： | 国家自然科学基金资助项目No.39070862 |
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| 摘 要： | 研究了Ｐ物质受体在豚鼠听觉脑干中枢及内侧膝状体的分布。采用兔抗ＳＰＲ血清和免疫组织化学ＡＢＣ法及葡萄糖氧化酶－ＤＮＡ－镍染色技术。结果；耳蜗核，上橄榄复合体，下丘及内侧膝状体广泛分布ＳＰＲ理性神经元，纤维及终末。
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| 关 键 词： | P物质受体 脑干听觉中枢 膝状体 |
Distribution of SP receptor immunoreactive positive products in the brain stem auditory centre and medial geniculate body of guinea pigs |
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| Qiu Jianhua,Wang Jinling,Shi Jiwu,Li Yunqing,Liu Shunli.Distribution of SP receptor immunoreactive positive products in the brain stem auditory centre and medial geniculate body of guinea pigs[J].Journal of the Fourth Military Medical University,1997,18(1):9-12. |
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| Authors: | Qiu Jianhua Wang Jinling Shi Jiwu Li Yunqing Liu Shunli |
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| Institution: | Qiu Jianhua,Wang Jinling,Shi Jiwu,Li Yunqing,Liu ShunliDepartment of Otorhinolaryngology,Xijing Hospital,Fourth Military Medical University,Xi'an 710033 Department of Anatomy,Fourth Military Medical University |
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| Abstract: | Objective:To investigate the distribution of substance P receptor (SPR) in the brain stem auditory centre and medial geniculate body (MGB) of guinea pigs. Methods: Rabbit serum against SPR. immuno-histochemical ABC method and glucose-oxidase-DAB-nickle technique were used in this study. Results: The positive neurons, fibers and endings of SPR were distributed widely in the cochlear nucleus, superior olive complex, inferior colliculus and MGB. In cochlear nucleus, SPR positive neurons were distributed mainly in the ventral cochlear nucleus (VCN). SPR positive products were located predominately in the cell membrane. The density of positive endings in the dorsal cochlear nucleus (DCN) was higher than that in the ventral cochlear nucleus. There were obvious characteristics in distribution pattern of SPR positive products in the superior olive complex. The positive neurons of SPR were located mainly in lateral superior olive. In the central nucleus of inferior colliculus, SPR positive fibers, endings and neurons were also found, but the number of positive neurons was fewer. The density of SPR positive fibers and endings in the MGB was higher. Conclusion: SP may participate in transmitting sound messages in brain stem auditory centre and MGB of guinea pig. |
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| Keywords: | substance P receptor immunohistochemistry brain stem auditory centre guinea pig |
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