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A Randomized Trial of Heparin and Saline for Maintaining Intravenous Locks in Neonates |
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| Authors: | Joni Heilskov MA RN CNNP Charmaine Kleiber PhD RN Karen Johnson BSN RN June Miller BSN RN |
| Institution: | Joni Heilskov, MA, RN, CNNP, is a Pediatric Nurse Practioner;Charmaine Kleiber, PhD(C), RN, is a Research Nurse Specialist;Karen Johnson, BSN, RN, is an Assistant Nurse Manager;and June Miller, BSN, RN, is CMV Study Nurse Coordinator, University of Iowa Hospitals and Clinics, Iowa City, IA. |
| Abstract: | purpose . To determine, the effects of saline, heparin 2 units (U) per ml saline, and heparin 10 U/ml saline flush solutions on the duration of intravenous (IV) locks and the incidence of IV infiltration in neonates. design.design. Randomized double-blind experiment. setting.setting. Tertiary-care nursery. participants.participants. Neonates (N = 90) hospitalized at birth in the intensive, intermediate care, or newborn units. main outcome measures.main outcome measures. Total hours from the time the IV was inserted to the time the IV was removed; hours from the time the IV was first flushed to the time the IV was removed; number of IVs removed because of infiltration. results.results. No statistical or clinical differences between the three groups for duration of IV nor for incidence of complications. conclusions.conclusions. The use of heparin in IV lock flush solution did not affect the duration of IV locks nor the incidence of infiltration in neonates. |
| Keywords: | Heparin neonate peripheral catheterization |