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Improve efficacy of topical ALA-PDT by calcipotriol through up-regulation of coproporphyrinogen oxidase
Affiliation:1. Department of Bioscience Technology, Chung Yuan Christian University, Taoyuan, Taiwan, ROC;2. Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan, ROC;3. Department of Dentistry, National Taiwan University Hospital, College of Medicine, Taipei, Taiwan, ROC;4. University of Colorado Denver Cancer Center, CO, USA;5. Department of Life Science, Tzu Chi University, Hualien, Taiwan, ROC;6. Department of Oral and Maxillofacial Surgery, Mackay Memorial Hospital, Taipei, Taiwan;7. Institute of Biomedical Sciences, Mackay Medical College, Taipei, Taiwan;8. Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan;9. Institute of Oral Biology and Department of Dentistry, School of Dentistry, National Yang-Ming University, Taipei, Taiwan;10. Department of Pathology and Laboratory Medicine, Taoyuan Armed Force General Hospital, Taiwan;11. Center for Nanotechnology, Chung Yuan Christian University, Taoyuan, Taiwan, ROC;12. Institute of Biomedical Technology, Chung Yuan Christian University, Taoyuan, Taiwan, ROC;1. Department of Ophthalmology, First Hospital of China Medical University, Shenyang, People''s Republic of China;2. Georgetown University School of Medicine, Washington, DC, USA;1. Department Excitable Structures, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Street, Bldg. 21, 1113, Sofia, Bulgaria;2. J. Heyrovský Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, Dolejškova 3, 182 23 Praha 8, Czech Republic;3. Department of Anesthesiology and Intensive Care, Military Medical Academy, Sveti Georgi Sofiyski Street 3, 1606 Sofia, Bulgaria;4. Department of Surgery, Military Medical Academy, Sveti Georgi Sofiyski Street 3, 1606, Sofia, Bulgaria;5. Department Molecular Biology of Cell Cycle, Institute of Molecular Biology, Bulgarian Academy of Sciences, Acad. G. Bonchev Street, bl. 21, 1113 Sofia, Bulgaria;1. School of Pharmacy & Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), Tianjin Medical University, Tianjin, 300070, China;2. School of Dentistry & Hospital of Stomatology, Tianjin Medical University, Tianjin, 300070, China;1. University Hospital of Lille – CHRU, Lille F59000, France;2. Université de Lille 2, Lille F59000, France;3. Inserm, U703 – ThIAIS, Loos F59120, France;1. Restorative Dentistry Departament, Universidade Federal de Minas Gerais (UFMG), Avenida Antônio Carlos 6627, CEP 31270-901 Belo Horizonte, Brazil;2. Centro de Pesquisas René Rachou, Fundação Osvaldo Cruz, Avenida Augusto de Lima 1715, CEP 30190-002 Belo Horizonte, Brazil;3. Restorative Dentistry Departament, Dentistry Faculty, Universidade de São Paulo, Prof. Lineu Prestes, 2227, CEP 05508-000 São Paulo, Brazil
Abstract:
Keywords:Topical photodynamic therapy  Oral precancerous lesions  Calcipotriol  5-Aminolevulinic acid  Hamster buccal pouch precancer
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