Role of parental occupation in autism spectrum disorder diagnosis and severity |
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| Affiliation: | 1. Division of Epidemiology, Human Genetics and Environmental Sciences (EHGES), The University of Texas School of Public Health at Houston, USA;2. Biostatistics/Epidemiology/Research Design Core, Center for Clinical and Translational Sciences (CCTS), The University of Texas Health Science Center at Houston, Houston, TX 77030, USA;3. Department of Psychiatry and Behavioral Sciences, The University of Texas Medical School at Houston, Houston, TX 77030, USA;4. Department of Pediatrics, Children''s Learning Institute, and the Division of Child and Adolescent Neurology, University of Texas Health Science Center at Houston, Houston, TX 77030, USA;1. Centre de Recherches en Psychologie, Cognition et Communication (EA 1285), Université Rennes 2, Place du Recteur Henri Le Moal, 35000 Rennes, France;2. Unité de Recherche Interdisciplinaire (EA 4156) Octogone-ECCD, Université Toulouse 2, Pavillon de la Recherche, 5 Allées A. Machado, 31058 Toulouse Cedex 9, France;3. Unité de Recherche Interdisciplinaire (EA 4156) Octogone-CERPP, Université Toulouse 2, Pavillon de la Recherche, 5 Allées A. Machado, 31058 Toulouse Cedex 9, France;4. San Diego State University, 5500 Campanile Drive, San Diego, CA 92182-4611, USA;1. Department of Psychology and Cognitive Science, University of Trento, Rovereto, Italy;2. Department of Computational Biology, Research and Innovation Centre, Fondazione Edmund Mach (FEM), San Michele all’Adige, Italy;1. School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan;2. Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan;3. Division of Occupational Science and Occupational Therapy, University of Southern California, 1540 Alcazar Street, Los Angeles, CA 90089, USA;1. Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia;2. Department of Community Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia;3. Department of Psychiatry, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia;1. Division of Rheumatology, Allergy, and Clinical Immunology, Department of Internal Medicine, University of California, Davis, 451 E Health Sciences Drive, Suite 6510 GBSF, Davis, CA 95616, USA;2. NIEHS Center for Children''s Environmental Health, University of California, Davis, USA;3. The M.I.N.D. Institute, University of California, Davis, USA;1. Department of Psychology, Swansea University, Swansea SA28PP, United Kingdom;2. Rehabilitation Institute, Southern Illinois University, Carbondale, Mailcode 4609, Carbondale, IL 62901, United States;3. School of Psychology, University College Dublin, Belfield, Dublin 4, Ireland;4. School of Psychology, University of South Wales, Pontypridd CF371DL, United Kingdom |
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| Abstract: | Some have suggested that parents of children with autism spectrum disorder (ASD) may present with less recognizable autistic-like phenotypic characteristics, leading them to highly systemizing occupations. Using secondary analysis of data from two previous studies of children with ASD, we tested associations between parental occupations and ASD diagnosis and the association of parental occupational characteristics on ASD severity. We found that fathers in healthcare (P < 0.01) and finance (P = 0.03) were more likely to have children with ASD. Additionally, joint effects of parental technical occupations were associated with communication (P < 0.01) and social impairment (P = 0.04). These results support that a “broader phenotype” and possible assortative mating in adults with autistic-like characteristics might contribute to intergenerational transmission and having offspring with greater ASD severity. |
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| Keywords: | Autism Diagnosis Severity Risk Occupation Parents |
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