Whole-slide imaging: widening the scope of cytopathology |
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| Affiliation: | 5. Department of Pathology, Linköping University Hospital, Linköping, Sweden;1. T2i Interaction Laboratory, Department of Applied Information Technology, Chalmers University of Technology, Göteborg, Sweden;2. Centre for Image Science and Visualization, Linköping University, Linköping, Sweden;3. Department of Science and Technology, Linköping University, Linköping, Sweden;4. Sectra AB, Linköping, Sweden;1. Department of Pathology and Anatomical Sciences, University at Buffalo, The State University of New York, 100 High Street, Buffalo, New York;2. Department of Electrical Engineering, University at Buffalo, The State University of New York, Buffalo, New York;3. Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, New York |
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| Abstract: | Whole slide imaging (WSI) is broadening the scope of cytopathology. Whole slide images are being used for telecytology, quality assurance activities (e.g. proficiency testing) and teaching (e.g. digital teaching sets and online virtual atlases). Progress in WSI technology that permits high resolution scanning, z-stacking, and hybrid robotic devices has encouraged the use of this imaging modality for cytology practice, education and research. However, widespread adoption in cytology still depends on overcoming barriers unrelated to cytology and challenges directly related to digitizing cytopathology slides. The aim of this article is to review WSI technology, applications and limitations specific to cytopathology. |
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| Keywords: | cytology digital pathology informatics proficiency testing telecytology whole slide imaging z-stacking |
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