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鹿茸人参制剂的毒理学安全性评价
引用本文:隋海霞,高芃,耿桂英,刘海波,汪会玲,徐海滨.鹿茸人参制剂的毒理学安全性评价[J].现代预防医学,2007,34(23):4448-4450.
作者姓名:隋海霞  高芃  耿桂英  刘海波  汪会玲  徐海滨
作者单位:中国疾病预防控制中心营养与食品安全所,北京,100021
摘    要:目的]了解鹿茸人参制剂的安全性。方法]小鼠急性经口毒性试验,Ames试验,小鼠骨髓嗜多染红细胞微核试验,小鼠精子畸形试验,大鼠30 d喂养试验。结果]该制剂急性经口毒性为无毒,在三项遗传毒性试验中均为阴性结果,在30 d喂养试验中也无异常发现。结论]鹿茸人参制剂安全无毒。

关 键 词:鹿茸人参制剂  安全性  试验
文章编号:1003-8507(2007)23-4448-03
修稿时间:2006年12月28

SAFETY EVALUATION OF PREPARATION OF PILOSE ANTLER AND GINSENG IN TOXICOLOGY
SUI Hai-xia,GAO Peng,GENG Gui-ying,et al..SAFETY EVALUATION OF PREPARATION OF PILOSE ANTLER AND GINSENG IN TOXICOLOGY[J].Modern Preventive Medicine,2007,34(23):4448-4450.
Authors:SUI Hai-xia  GAO Peng  GENG Gui-ying  
Abstract:Objective]To study the safety of the preparation of pilose antler and ginseng.Methods]Used the acute toxicity test in mice,Ames test,micronuclei test of bone marrow cell,sperm shape abnormality test in mice and 30 days feeding test in rats.Results]The preparation of pilose antler and ginseng had no acute toxicity.All three genetic toxicity tests had negative results.Abnormal phenomena were not found in 30 days feeding test.Conclusion]The preparation of pilose antler and ginseng is safe to use.
Keywords:Preparation of pilose antler and ginseng  Safety  Test
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