注射用益气复脉（冻干）治疗慢性心力衰竭伴低血压的临床研究

目的 探究注射用益气复脉（冻干）治疗慢性心力衰竭伴低血压的临床应用价值。方法 回顾性选取2019年7月—2021年3月于泰山医学院鲁西医院住院治疗的80例慢性心力衰竭伴低血压患者为研究对象，按照患者治疗方法不同分为对照组和观察组，每组各40例，对照组针对原发性疾病进行常规治疗，观察组在对照组的基础上给予注射用益气复脉（冻干）治疗，5.2 g加入5%葡萄糖注射液或0.9%氯化钠注射液500 mL中静脉滴注，1次/d，连续治疗14 d。观察两组患者的临床疗效，同时比较两组患者治疗前后心功能指标和血压变化情况。结果 治疗后，观察组总有效率为95%，显著高于对照组的80%，两组比较差异有统计学意义（P<0.05）。治疗后两组左心室射血分数（LVEF）、舒张压和收缩压均升高，N端脑钠肽前体（NT-proBNP）降低，两组间治疗后对比差异有统计学意义（P<0.05）。结论 注射用益气复脉（冻干）治疗慢性心力衰竭伴低血压效果理想，患者血压水平升高，心功能改善。

Clinical study on Yiqi Fumai Lyophilized Injection in treatment of chronic heart failure with hypotension

Objective To explore the clinical value of Yiqi Fumai Lyophilized Injection in the treatment of chronic heart failure with hypotension. Methods Total 80 patients with chronic heart failure and hypotension hospitalized in Luxi Hospital of Taishan Medical College from July 2019 to March 2021 were retrospectively selected as the research object. According to different treatment methods, the patients were divided into control group and observation group, with 40 cases in each group. Patients in the control group received routine treatment for primary diseases, and patients in the observation group were given Yiqi Fumai Lyophilized Injection on the basis of the control group for treatment, 5.2 g was added with 5% glucose injection or 0.9% sodium chloride injection 500 mL intravenously, once a day for 14 days. The clinical effects of two groups were observed, and the changes of cardiac function indexes and blood pressure were compared between two groups before and after treatment. Results After treatment, the total effective rate of the observation group was 95%, significantly higher than 80% of the control group. There was significant difference between the two groups (P<0.05). After treatment, left ventricular ejection fraction (LVEF), diastolic and systolic blood pressure increased, and N-terminal pro brain natriuretic peptide (NT proBNP) decreased. There was significant difference between two groups after treatment (P<0.05). Conclusion Yiqi Fumai Lyophilized Injection is effective in the treatment of chronic heart failure with hypotension. The blood pressure level of patients increases and the cardiac function improves.