Validation of the Face Name Associative Memory Exam in cognitively normal older individuals |
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| Authors: | Rebecca E Amariglio Katherine Frishe Lauren E Olson Lauren P Wadsworth Natacha Lorius Reisa A Sperling Dorene M Rentz |
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| Affiliation: | Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA. ramariglio@partners.org |
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| Abstract: | The recently developed Face Name Associative Memory Exam (FNAME), a challenging paired associative learning task, shows promise in detecting the subtle cognitive changes characteristic of preclinical Alzheimer's disease. In this study, we evaluated the validity and reliability of the FNAME in 210 cognitively normal older individuals (58-90 years of age). Construct validity of the measure was assessed by principal components analysis, which revealed two independent factors. Correlations between the FNAME subtests and another episodic memory test were significant. The results indicated strong test-retest reliability in a subsample (n = 41). Normative data stratified by age were also generated. |
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