| 蟾酥透皮吸收研究 |
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| 引用本文： | 虞金宝,程怡,金克宁,冯青.蟾酥透皮吸收研究[J].中国中药杂志,1995,20(9):539-541. |
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| 作者姓名： | 虞金宝 程怡 金克宁 冯青 |
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| 作者单位： | 江西省中医药研究所 南昌 330006,**江西省铁路中心医院药剂科 南昌 330000 |
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| 基金项目： | 国家自然科学基金，江西省自然科学基金 |
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| 摘 要： | 以V-C扩散池和HPLC检测法,研究丙二醇和Azone对蟾酥的透皮吸收影响;并对脂蟾毒配基进行了HPLC定量检测。结果表明:丙二醇能明显增强脂蟾毒配基的透皮吸收,Azone能明显缩短其透皮时滞。
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| 关 键 词： | 蟾酥 脂蟾毒配基 透皮吸收 丙二醇 Azone |
| 收稿时间： | 1994/11/8 0:00:00 |
Studies on Percutaneous Alsorption of Venenuin Bufonis in Vitro |
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| Yu Jinhao;Cheng Yi; Feng Qing;Jin Kening.Studies on Percutaneous Alsorption of Venenuin Bufonis in Vitro[J].China Journal of Chinese Materia Medica,1995,20(9):539-541. |
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| Authors: | Yu Jinhao;Cheng Yi; Feng Qing;Jin Kening |
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| Abstract: | V-C horizontal diffusion cell and HPLC determination have been utal to study the effect of 1, 2-propanediol and azone on the percutaneous absrption Venenum Bufonis the contents of resibufogenin have been deter-nnned through mouse skin in vitro by HPLC. The results indicate that the contents get increased when 1, 2-propanedi-ol is added and that azone can shorten the lag time of percutaneous abasorption of resibufogenin through mouse skin invitro. |
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| Keywords: | Venenum Buforus resibufogenin percutaneous absorption 1 2-propanediof azone |
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