党参口服液治疗25例冠心病血瘀证患者临床及实验研究

以２１名健康人及５２例冠心病血瘀证患者为对象，用发色底物法测定其血浆组织型纤溶酶原激活物（ｔ－ＰＡ）及其抑制（ＰＡＩ）活性变化，结果表明，冠心病血瘀证患者血浆ｔ－ＰＡ活性明显降低，与健康人比较，有显著性意义（Ｐ＜０．０１）。又经党参口服液对２５例冠心病气虚血瘀症患者轿浆ｔ－ＰＡ活性及以及血小板聚集功能的治疗观察，发现治疗后，血小板聚集功能明显降低，而对ｔ－ＰＡ及ＰＡＩ活性无明显影响。提示党参口服液

Clinical and Experimental Study on Codonopsis Pilosula Oral Liquor in Treating Coronary Heart Disease with Blood Stasis

The effects of Codonopsis pilosula oral liquor(CPOL) on tissue-type plasminogen activator(t PA) and plasminogen activator inhibitor(PAI) in the plasma of 25 patients of coronary heart disease with blood stasis were studied.It has been shown that those patients had a significant decrease in t-PA activity(P<0.01) compared to healthy subjects.After 4 weeks of CPOL therapy,platelet aggregation significantly decreased(p<0.05).there was no significant difference in t-PA and PAI.From the results shown above,it suggested that one of the effects of CPOL in influencing blood coagulation was its inhibition on platelet aggregation,but not through the elevating of fibrinolytic activity.