Interplay of vitamin D,vitamin B12, homocysteine and bone mineral density in postmenopausal females |
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| Authors: | Sundus Tariq Saba Tariq Khalid Parvez Lone |
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| Institution: | 1. Assistant Professor Physiology, University Medical and Dental College, Faisalabad, Pakistan;2. PhD Scholar Physiology, University of Health Sciences, Lahore, Pakistandr.sundustariq@gmail.com;4. Assistant Professor Pharmacology, University Medical and Dental College, Faisalabad, Pakistan;5. PhD Scholar Pharmacology and Therapeutics, University of Health Sciences, Lahore, Pakistan;6. Department of Physiology/ Metabolic Disorders, University of Health Sciences, Lahore, Pakistan |
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| Abstract: | ABSTRACTOsteoporosis is most common age related, multifactorial disease. The aim of the researchers were to discover the association between serum homocysteine, vitamin D, vitamin B12 and bone mineral density in postmenopausal non-osteoporotic and osteoporotic females. In this cross- sectional study, 156 postmenopausal females between 50–70 years of age were recruited and divided into two groups, non-osteoporotic (n = 52) and osteoporotic (n = 104). There was significant negative correlation of homocysteine with vitamin D and B12 in postmenopausal non-osteoporotic and homocysteine with vitamin B12 in postmenopausal osteoporotic females. Serum homocysteine levels were predicted by vitamin D in postmenopausal non-osteoporotic and vitamin B12 in postmenopausal osteoporotic females. |
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