Carcinosarcomatous malignancy, osteosarcoma and squamous cell carcinoma, in giant cell tumor of the right distal femur |
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Authors: | Machinami Rikuo Nishida Kazunori Ishida Tsuyoshi Matsumoto Seiichi Kuroda Kouji Kobayashi Masafumi Takeuchi Kengo Ishikawa Yuichi |
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Institution: | Department of Pathology, Cancer Institute, Japanese Foundation for Cancer Research, Ariake 3-10-6, Kouto-ku, Tokyo 135-8550, Japan. machinami-tky@umin.ac.jp |
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Abstract: | We report a new type of secondary malignant giant cell tumor of bone, the malignancy of which was assigned to a carcinosarcoma, i.e., osteosarcoma and squamous cell carcinoma. It occurred 25 years after curettage and bone graft surgery under the diagnosis of giant cell tumor of the right distal femur. Although secondary malignant giant cell tumor is known as a sarcoma arising at the site of a previously diagnosed giant cell tumor, this case should be regarded as a new type of secondary malignant giant cell tumor of bone. |
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Keywords: | Giant cell tumor Carcinosarcoma Squamous cell carcinoma Osteosarcoma |
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