| 卡络磺钠注射液含量测定方法研究 |
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| 引用本文： | 张荣桂,吕伟,马鸿雁. 卡络磺钠注射液含量测定方法研究[J]. 中国药业, 2008, 17(6): 33-34 |
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| 作者姓名： | 张荣桂 吕伟 马鸿雁 |
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| 作者单位： | 山东省枣庄市药品检验所,山东,枣庄,277102 |
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| 摘 要： | 目的用高效液相色谱（HPLC）法测定卡络磺钠注射液的含量。方法采用C18柱，流动相为醋酸及醋酸钠缓）中液（取醋酸钠10．2g，加冰醋酸40mL，再加水稀释至500mL）-甲醇（90：10），检测波长为363nm。结果方法平均回收率及RSD分别为99.82％和0.49％（n=6）。结论HPLC法简便、准确，适用于该产品的质量分析。
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| 关 键 词： | 高效液相色谱法 卡络磺钠 含量测定 |
| 文章编号： | 1006-4931（2008）06-0033-02 |
| 收稿时间： | 2007-07-05 |
| 修稿时间： | 2007-09-30 |
Determination of Carbazochrome Sodium Sulfonate in Carbazochrome Sodium Sulfonate Injection by HPLC |
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| Zhang Ronggui,Lv Wei,Ma Hongyan. Determination of Carbazochrome Sodium Sulfonate in Carbazochrome Sodium Sulfonate Injection by HPLC[J]. China Pharmaceuticals, 2008, 17(6): 33-34 |
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| Authors: | Zhang Ronggui Lv Wei Ma Hongyan |
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| Affiliation: | (Zaozhuang Institute for Drug Control, Zaozhuang, Shandong, China 277102) |
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| Abstract: | Objective To establish a method for the determination of earbazoehrome sodium sulfonate in earbazochrome sodium sulfonate injection by HPLC. Methods Cts column was selected and the mobile phase consisted of acetic acid and sodium acetate buffer-methanol （90： 10）, the wavelength of detection was 363 nm. Results The average recovery rate was 99.82%, RSD was 0. 49% （n=6）. Conclusion The method can be used to determine the concentration of earbazoehrome sodium sulfonate injection rapidly and accurately. |
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| Keywords: | HPLC carbazochrome sodium sulfonate content determination |
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