| 清源调脂胶囊对大鼠实验性动脉粥样硬化形成的影响 |
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| 引用本文： | 李文彪,石瑞丽.清源调脂胶囊对大鼠实验性动脉粥样硬化形成的影响[J].包头医学院学报,2002,18(1):1-3. |
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| 作者姓名： | 李文彪 石瑞丽 |
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| 作者单位： | 包头医学院中医药临床应用研究所,内蒙古,包头,014010 |
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| 摘 要： | 目的：探讨清源调脂胶囊对大鼠实验性动脉样硬化形成的影响。方法：高脂饲料喂养建立大鼠动脉粥样硬化模型，治疗组大鼠同步给予源调脂胶囊，对照组大鼠同步给予月见草油胶丸，检测各组大鼠血脂液脂质和血清MDA含量及肝脏MDA含量，并观察主动脉组织结构变化，结果：与模型组相比，治疗组、对照组大鼠的TC、TG、LDL－c及MDA等均显著下降，尤以治疗组大鼠为最；治疗组大鼠主动脉粥样硬化程度明显减轻，结论：清源调脂胶囊能有效降低大鼠TC、TG、LDL－c及MDA含量，并对动脉粥样硬化早期病产生明显的抑制作用。
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| 关 键 词： | 清源调脂胶囊 动脉粥样硬化 血脂 药理 治疗 |
| 文章编号： | 1006-740X(2002)01-0001-03 |
| 修稿时间： | 2001年12月20日 |
ffects of Qingyuan Tiaozhi(QYTZ) Capsule on the Formation of Experimental Arteriosclerosis in Rats |
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| Li Wenbiao,Shi Ruili.ffects of Qingyuan Tiaozhi(QYTZ) Capsule on the Formation of Experimental Arteriosclerosis in Rats[J].Journal of Baotou Medical College,2002,18(1):1-3. |
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| Authors: | Li Wenbiao Shi Ruili |
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| Abstract: | Objective:To explore the effect of QYTZ capsule on the formation of experiment arteriosclerosis in rats. Methods:Experiment arteriosclerosis model was established by feeding rats with high fat diet, simutaneously, QYTZ capsule and Oenothera Biennis L pill were given to rats in treatment group and control group respectively, then the following indexes were detected in each group: the serum lipid, MDA content in serum and liver, and the changes in aorta histology. Results: Compared with the model group, QYTZ capsule group and Oenothera Biennis L pill group have a marked reduction in serum TC, TG, LDL c and MDA and the effects of QYTZ capsule were much more significant, it also alleviated the degree of arteriosclerosis obviously. Conclusions: QYTZ capsule has a remarkable effect of reducing TC, TG, LDL c and MDA, so it may prevent arteriosclerosis effectively. |
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| Keywords: | QYTZ capsule serum lipid arteriosclerosis |
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