| 桃核承气汤对热瘀证大鼠SOD、MDA的影响 |
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| 引用本文： | 徐晓东,殷子杰,孔丽娅,何赛萍. 桃核承气汤对热瘀证大鼠SOD、MDA的影响[J]. 河南中医, 2005, 25(9): 20-21 |
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| 作者姓名： | 徐晓东 殷子杰 孔丽娅 何赛萍 |
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| 作者单位： | 浙江中医学院,浙江,杭州,310053 |
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| 基金项目： | 浙江省教育厅科研基金资助项目（编号：20030941）：浙江省中医管理局科研基金资助项目（编号：2000C02） |
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| 摘 要： | 目的：观察桃核承气汤对热瘀证大鼠SOD、MDA的影响，探讨其对血管内皮细胞损伤的保护作用。方法：采用大肠杆菌内毒素复制大鼠内毒素性热瘀证模型，于首次注入内毒素前1h、注入后12h、第2次注入内毒素前1h分别灌胃桃核承气汤浓缩液，检测桃核承气汤对SOD、MDA的影响。结果：桃核承气汤能增强热瘀证大鼠模型SOD的活性，抑制热瘀证大鼠MDA含量的增加。
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| 关 键 词： | 桃核承气汤 蓄血证 大鼠 超氧化物歧化酶 丙二醛 |
| 文章编号： | 1003-5028(2005)09-0020-02 |
| 收稿时间： | 2005-05-20 |
| 修稿时间： | 2005-05-20 |
Influence of Taohe Chengqi Decoction on SOD and MDA of Rats with Heart Stagnation Syndrome |
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| Xu Xiaodong,Yin Zijie,Kong Liya,He Saiping. Influence of Taohe Chengqi Decoction on SOD and MDA of Rats with Heart Stagnation Syndrome[J]. Henan Traditional Chinese Medicine, 2005, 25(9): 20-21 |
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| Authors: | Xu Xiaodong Yin Zijie Kong Liya He Saiping |
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| Abstract: | Objective: To observe the influence of Taohe Chengqi Decoction on SOD and MDA of rats with heart stagnation syndrome, and to probe the decoction's protective action on the vascular endotheliocyte vascular. Methods: Colibacillus endotoxin was taken to duplicate the endotoxic model rats with heat stagnation syndrome. The concentrated solution of Taohe Chengqi Decoction was poured into the rat's stomach respectively an hour before the endotoxin injection for the first time, 12 hours after the injection and an hour before the injection for the second time to examine the influence of Taohe Chengqi Decoction on rats' SOD and MDA. Results: Taohe Chengqi Decoction could strengthen the SOD vitality of modelled rats with heat stagnation syndrome and restrain the increase of MDA content of rats with heat stagnation syndrome. |
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| Keywords: | Taohe Chengqi Decoction syndrome of blood retention rats SOD MDA |
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