| 均匀设计法优选莲子心的半仿生提取工艺 |
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| 引用本文： | 袁小红,赵瑞芝,丘小惠. 均匀设计法优选莲子心的半仿生提取工艺[J]. 中国药房, 2005, 16(21): 1618-1620 |
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| 作者姓名： | 袁小红 赵瑞芝 丘小惠 |
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| 作者单位： | 广州中医药大学第二临床医学院,广州市,510120 |
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| 基金项目： | 广东省中医药管理局科研项目 |
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| 摘 要： | 目的:优选半仿生法提取莲子心中总生物碱的工艺条件。方法:采用均匀设计法优选半仿生提取工艺;以总生物碱含量、干 浸膏得率为指标,考察药材的提取时间、溶媒量、pH值等因素对提取工艺的影响。结果:优选工艺为莲子心加8倍量水提取3次,3 煎用水的pH值分别为5．0、6．0、8．0,煎煮总时间为4h。结论:本法为莲子心的提取提供了理论依据。
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| 关 键 词： | 莲子心 均匀设计法 半仿生提取法 工艺条件 |
| 文章编号： | 1001-0408（2005）21-1618-03 |
| 收稿时间： | 2005-04-20 |
| 修稿时间： | 2005-06-13 |
Technical Condition for Semi - bionic Extraction of Plumula Nelumbinis by Homogenous Design |
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| YUAN Xiaohong,ZHAO Ruizhi,QIU Xiaohui. Technical Condition for Semi - bionic Extraction of Plumula Nelumbinis by Homogenous Design[J]. China Pharmacy, 2005, 16(21): 1618-1620 |
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| Authors: | YUAN Xiaohong ZHAO Ruizhi QIU Xiaohui |
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| Affiliation: | The Second College of Clinical Medicine, Guangzhou University of TCM, Guangzhou 510120, China |
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| Abstract: | OBJECTIVE: To optimize the extraction conditions of plumula nelumbinis. METHODS: The semi - bionic extraction (SBE) conditions were optimized by homogeneous design while total alkaloids and dry extract were adopted as markers. Factors of extraction time, solute quantity and the pH values were evaluated for their effects on extraction process. RESULTS: Optimal parameters were as follows: plumula nelumbinis was extracted in water 8 times as much as it for 3 times; the pH values of the water for the 1st, 2nd and 3rd decoctions were 5.0,6.0 and 8.0, respectively; the boiling lasted 4 hours. CONCLUSION: The method prouides theoretical reference for the extraction plumula nelumbinis. |
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| Keywords: | Plumula nelumbinis Homogeneous design Semi-bionic extraction Extraction condition |
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