氨溴索与大剂量地塞米松治疗胎粪吸入综合征疗效观察

目的 观察氨溴索与大剂量地塞米松治疗新生儿胎粪吸入综合征的疗效.方法 60例新生儿胎粪吸入综合征患儿随机分为治疗组30例和对照组30例,治疗组在常规治疗基础上加用氨溴索与大剂量地塞米松治疗.结果 治疗组总有效率90.00%,对照组总有效率73.33%,两组比较差异有统计学意义（P〈0.05）.治疗组紫绀消退时间（1.85±0.65）d]和氧疗时间（3.21±1.42）d]较对照组缩短,两组比较差异有统计学意义（P〈0.01）.结论 氨溴索与大剂量地塞米松治疗新生儿胎粪吸入综合征疗效显著,安全性高,值得临床推广.

An observation on effect of ambroxol and high - dose dexamethasone in treatment of neonatal meconium aspiration syndrome

Objective To observe the Ambroxol and High - dose dexamethasone treatment in neonatal meconinm aspiration syndrome, netbods Sixty cases of neonatal meconium aspiration syndrome were randomly divided into a treatment group（30 cases） and a control group（30 cases） ,with the treatment group having ambroxol and high -dose dexamethasone in addition to the conventional therapy in treatment. Results The total effective rate of the treatment group was 90.00%, the control groups effectiveness was 73.33 %. The difference had statistical significance （P 〈 0.05 ）. In the treatment group, cyanosis time （1.85 ± 0.65）d] and oxygen therapy time （3.21 ± 1.42）d] were shorter than those in the control group. The difference between the two groups had statistical significane （ P 〈 0.01 ）. Conclusion Injection ambroxol and high - dose dexamethasone treatment of neonatal meconium aspiration syndrome is effective, safe and worth popularizing.