尼可地尔对稳定型心绞痛患者心功能的影响 |
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引用本文: | 陈艳丽,李爱国.尼可地尔对稳定型心绞痛患者心功能的影响[J].中国现代医生,2011,49(34):73-74. |
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作者姓名: | 陈艳丽 李爱国 |
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作者单位: | 衡阳市第五医院心血管内科,湖南衡阳,421007 |
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摘 要: | 目的 探讨尼可地尔对稳定性心绞痛患者心功能的影响。方法 观察50例稳定性心绞痛患者尼可地尔治疗1个月前后心功能指标的变化。结果 尼可地尔治疗1月后,稳定性心绞痛患者N终端脑钠肽前体(430.12±58.11)pg/mL VS (150.65±42.32)pg/mL,(t=2.77,P〈0.01)下降,射血分数(42.15±6.16) VS (52.36±9.20),(f=2.25,P〈0.05)及E/A峰比值(0.89±0.24) VS (1.22±O.12),(t=2.21,P〈0.05)均有升高。结论 尼可地尔在减少稳定型心绞痛患者心绞痛发作同时,可改善稳定性心绞痛患者心功能。
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关 键 词: | 尼可地尔 稳定性心绞痛 心功能 |
Effects of Nicorandil on Heart Function in Peoples with Stable Angina Pectoris |
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Authors: | CHEN Yanli LI Aiguo |
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Institution: | The Fifth Hospital of Hengyang City,Cardiovascular Medical,Hengyang 421007,China |
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Abstract: | Objective To study the effects of nicorandil on heart function in patients with stable angina pectoris before and after Nicorandil treatment. Methods We measured the level of N-T proBNP, E/A, EF in 50 patients with stable angina pectoris before and after I month of treatment course with Nicorandil. Results After nicorandil treatment, we found these were reduced levels N-T proBNP (430.12±58.11 pg/ml vs 150.65 ± 42.32 pg/ml, t=2.77, P〈O.01),and raised levels of EF (42.15 ±6.16 vs 52.36±9.20,t=2.25, P〈0.05) and E/A (0.89±0.24 vs 1.22 ±0.12, t=2.31, P〈O.05). Conclusion Nicorandil could enhance heart function in patients with stable angina pectoris. |
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Keywords: | Nicorandil Stable angina pectoris Heart function |
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