埃索美拉唑联合莫沙比利治疗反流性食管炎的临床研究 |
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引用本文: | 高杨. 埃索美拉唑联合莫沙比利治疗反流性食管炎的临床研究[J]. 海峡药学, 2016, 0(9): 87-89. DOI: 10.3969/j.issn.1006-3765.2016.09.034 |
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作者姓名: | 高杨 |
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作者单位: | 四川省建筑医院内三科成都610081 |
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摘 要: | 目的:评价埃索美拉唑联合莫沙比利治疗反流性食管炎安全性、有效性。方法2013年5月~2015年5月,观察组与对照组各入选40例GERD,分别采用埃索美拉唑联合莫沙必利、单独应用莫沙必利治疗,对比疗效、不良反应发生例。结果观察组痊愈率42.5%、愈显率92.5%高于对照组22.5%、60.0%,差异具有统计学意义(P<0.05);对照组未见不良反应,观察组出现1例骨质疏松症、1例胸痛,差异无统计学意义(P>0.05)。结论埃索美拉唑联合莫沙必利治疗GERD疗效较好,安全可靠。
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关 键 词: | 反流性食管炎 埃索美拉唑 莫沙必利 疗效 安全性 |
Clinical Study of Esomeprazole Combined with Mosapride in the Treat-ment of Reflux Esophagitis |
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Abstract: | OBJECTIVE To evaluate the safety and effectiveness of esomeprazole combined with mosapride in the treatment of reflux esophagitis.METHODS From May 2014 to May 2015 , the observation group and control group each selected 40 patients with GERD,observation group received esomeprazole combined with mosapride,con-trol group received mosapride treatment alone.The efficacy,adverse reactions occurred were compared.RESULTS The cure rate and the healing rate of the observation group were 42.5%and 92.5%,which were higher than that of the control group (22.5% and 60%),the difference was statistically significant (P<0.05).No adverse reactions were found in the control group,1 cases of osteoporosis and 1 cases of chest pain were observed in the observation group,there was no statistically significant difference (P >0.05).CONCLUSION The esomeprazole combined with mosapride in treatment of GERD has good curative effect and good safety. |
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Keywords: | Reflux esophagitis Esomeprazole Mosapride Efficacy Safety |
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