狗皮膏质量分析

目的：对狗皮膏进行质量分析评价。方法针对高温提取药味进行TLC和显微特征鉴别；针对原粉入药的药味进行 GC特征图谱研究和含量测定；应用AA测定家兔贴敷后血铅含量变化；应用UV法测定总羰基化合物含量。结果狗皮膏总体质量状况差，药品质量控制落后，产品质量问题棘手，个别企业未按工艺生产。结论建议：①研究大生产工艺迫在眉睫；②现行标准亟需提高；③限制膏药贴用时间。

Quality Analysis of Goupi Ointment

ABSTRACT:OBJECTIVE Analysis the quality of Goupi ointment.METHODS Aiming at the high extraction drugs TLC and microscopic characteristics identification;in the original powder medicine ingredients were determined the GC characteristic spectrum of research and content;AA was used to determine changes in blood lead levels after patching;Determination of total carbonyl compounds content by UV method.Skin cream quality analysis and evalua-tion.RESULTS The overall quality of the species is unsatisfactory due to the following reasons:serious problems were found in the drug production;drug quality control fell behind and some enterprises failed to produce drug according to technological standards.CONCLUSION Specific recommendations:①It is critical to research the production process;②It is urgent to improve the current control standard;③The service life of the patch should be specified.