| 火焰原子吸收分光光度法测定匹伐他汀钙中钙含量 |
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| 引用本文： | 刘丽鹤,黄华瑞,段永生,田洁,车宝泉. 火焰原子吸收分光光度法测定匹伐他汀钙中钙含量[J]. 中国药品标准, 2008, 9(6): 457-458 |
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| 作者姓名： | 刘丽鹤 黄华瑞 段永生 田洁 车宝泉 |
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| 作者单位： | 1. 北京双鹤药业股份有限公司,双鹤研究院,北京,100102
2. 北京市药品检验所,化学室,北京,100035 |
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| 摘 要： | 目的：建立了火焰原子吸收分光光度法测定匹伐他汀钙中钙含量。方法：采用钙空心阴极灯，检测波长422．7nm，狭缝宽0．7H，灯电流10mA。结果：钙元素浓度在0．00～20．00mg·L^-1范围内，浓度与吸光度相关性良好，r=0．9999，精密度RSD为0．3％，平均回收率为101．6％。结论：该方法操作简便、专属性强，可以为同类药物的馈量控制提供参考。
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| 关 键 词： | 火焰原子吸收分光光度法 匹伐他汀钙 钙 |
Determination of Calcium in Pitavastatin Calcium by Flame Atomic Absorption Spectrometry |
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| Liu Li-he,Huang Hua-rui,Duan Yong-sheng,Tian Jie and Che Bao-quan. Determination of Calcium in Pitavastatin Calcium by Flame Atomic Absorption Spectrometry[J]. , 2008, 9(6): 457-458 |
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| Authors: | Liu Li-he Huang Hua-rui Duan Yong-sheng Tian Jie Che Bao-quan |
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| Affiliation: | Liu Li-he1,Huang Hua-rui1,Duan Yong-sheng2,Tian Jie2,Che Bao-quan2(1.Department of Research,Double-crane pharmaceutical Co.LTD,Beijing 100102,2.Beijing Institute for Drug Control,Beijing 100035) |
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| Abstract: | Objectives：To establish a flame atomic absorption spectrometry for the determination of calcium in Pitavastatin Calcium. Methods：Calcium lamp was used with the wavelength at 422. 7nm. The slim width was set at 0. 7H. Results：The calibration range was from 0. 00 to 20. 00 mg·L^-1 , r =0. 999 9. The precision RSD was 0. 3% and the average recovery was 101.6%. Conclnsions：The method is simple and special, and it can be used for the quality control of statins. |
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| Keywords: | Flame atomic absorption spectrometry(FAAS) Pitavastatin calcium calcium |
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