甲状腺相关眼病诊断流程及治疗

甲状腺相关眼病（thyroidassociatedphthalmopathy，TAO）是一种器官特异性自身免疫性疾病，严重影响患者的生活质量，治疗效果欠佳，及时正确地认识和诊断本病是进一步治疗的关键。TAO的早期诊断需结合病史、一般检查、实验室检查及影像学检查等。正确评价病情的严重程度及活动性对决定采用何种治疗方式至关重要。轻度TAO多采取基础治疗；中、重度可选用糖皮质激素静脉冲击和眼眶放疗，必要时可行眼眶减压术；极重度TAO以糖皮质激素静脉冲击和眼眶减压手术为主。f国际眼科纵览，2012，36：341—345）

Diagnosis process and therapy in thyroid associated ophthalmopathy

Thyroid associated ophthalmology（TAO） is an organ-specific autoimmune disease. It can affect patient＇s quality of life and it is difficult to cure. So timely and exact knowledge and diagnosis of TAO is crucial to the further treatment. The early diagnosis of TAO needs to be combined with medical history, general examination, laboratory examination and imaging examination, etc. However, exact judgment on the activity and the severity of TAO is necessary, which is very important for determining the therapeutic meth- od. Local measures are recommended in mild TAO. Moderate-severe TAO is recommended to use intrave- nous glucocorticoids and orbital radiotherapy. Orbital decompression can be performed when necessary. In sight-threatening TAO is recommended to use intravenous glucocortieoids and orbital decompression. （Int Rev Ophthalmol, 2012, 36： 341-345）