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Chronic meningococcemia cutaneous lesions involve meningococcal perivascular invasion through the remodeling of endothelial barriers |
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| Authors: | Dupin Nicolas Lecuyer Hervé Carlotti Agnès Poyart Claire Coureuil Mathieu Chanal Johan Schmitt Alain Vacher-Lavenu Marie-Cécile Taha Muhamed-Kheir Nassif Xavier Morand Philippe C |
| Institution: | Université Paris Descartes, Sorbonne Paris Cité, Paris, France. |
| Abstract: | Chronic meningococcemia is a form of sepsis with frequent polymorphous skin lesions. Both in vivo and in vitro data suggest that, in these lesions, meningococci gain access from the capillary lumen to the peripheral extravascular compartment, in the absence of vascular dislocation, through a paraendothelial route. |
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