重度颅脑损伤患者低磷血症的发生率及其对预后的影响

目的：探讨重度颅脑损伤患者低磷血症的发生率及其对预后的影响.方法：回顾分析安徽省合肥市第二人民医院2010年10月-2012年3月收治的58例重度颅脑损伤患者的临床资料,选择60例同期健康体检者作为对照.比较重度颅脑损伤患者和健康体检者低磷血症的发生率及其预后.结果：重度颅脑损伤患者低磷血症的发生率[17.2％（10/58）]高于健康体检者[5.0％（3/60）],差异有统计学意义（P＜0.05）;重度颅脑损伤合并低磷血症患者的病死率为40.0％（4/10）,高于重度颅脑损伤但血磷正常者[10.4％（5/48）],差异有统计学意义（P＜0.05）;重度颅脑损伤低磷血症得到纠正者的病死率低于未得到纠正者,但差异无统计学意义（P＞0.05）.结论：重度颅脑损伤患者易发生低磷血症,合并低磷血症患者的病死率明显增加.

Incidence of Hypophosphatemia in Patients with Severe Craniocerebral Injury and Its Influence on Prognosis

Objective：To explore the incidence of hypophosphatemia in patients with severe craniocerebral injury and its influence on the prognosis.Methods：The clinical datum of 58 patients with severe craniocerebral injury treated in the Second People＇s Hospital of Hefei City from Oct 2010 to Mar 2012 were analyzed retrospectively.Sixty people who received health check-up were enrolled as control.Incidence of hypophosphatemia were compared between the two groups.Results：Incidence of hypophosphatemia in patients with severe craniocerebral injury was 17.2 ％ （10/58） and higher than that in health controls [5.0 ％（3/60）],P＜0.05.Amone severe craniocerebral injury patients,mortality rate hypophosphatemia was 40.0％ （4/10） and higher than that in cases with normal serum phosphorus[10.4 ％ （5/48）],P＜0.05.Mortality rate of severe craniocerebral injury patients with hypophosphatemia remedied was lower than without hypophosphatemia remedied,but there was no significant difference（P＞0.05）.Conclusions：Patients with severe craniocerebral injury are susceptible to hypophosphatemia,and the mortality rate of patients with severe craniocerebral injury combined with hypophosphatemia is higher than those without hypophosphatemia.