慢性阻塞性肺疾病评估测试问卷对慢性阻塞性肺疾病稳定期患者生活质量的评估价值

目的：探究慢性阻塞性肺疾病评估测试问卷（chronic obstructive pulmonary disease assessment test,CAT）对慢性阻塞性肺疾病（chronic obstructive pulmonary disease,COPD）稳定期患者生活质量的评估价值.方法：对40例COPD稳定期患者进行CAT评分以及圣乔治呼吸问卷（St George＇s respiratory questionnaire,SGRQ）评分,并测定体质量指数（BMI）、第1秒用力呼气容积/预计值（percentage of forced expiratory volume in 1 second in predicated value,FEV1％ pred）、改良的英国医学研究委员会呼吸困难量表（modified Medical Research Council dyspnea scale,MMRC）评分、6 min步行距离（six-minute walk distance,6MWD）、BODE（B为体质量指数,O为气道阻塞程度,D为呼吸困难分数,E为运动耐力）指数,并对结果进行相关性分析.结果：CAT评分与FEV1％pred、6MWD呈显著负相关（r分别为-0.71和-0.85,P＜0.01）,与MMRC评分、BODE指数呈显著正相关（r分别为0.78和0.83,P＜0.01）,与SGRQ总分及3个组成部分即呼吸症状、活动受限、疾病影响评分均呈显著正相关（r为0.92～0.97,P＜0.01）,与BMI无相关性.结论：CAT问卷可作为评估COPD稳定期患者生活质量的有效手段.

Evaluation Value of Chronic Obstructive Pulmonary Disease Assessment Test in Life Quality of Patients with Stable Chronic Obstructive Pulmonary Disease

Objective：To explore the evaluation value of chronic obstructive pulmonary disease assessment test（CAT） in life quality of patients with stable chronic obstructive pulmonary disease （COPD） in stationary phase.Methods：The CAT score,St George＇s respiratory questionnaire （SGRQ） score,body mass index （BMI）,percentage of forced expiratory volume in one second in predicated value （FEV1％pred）,modified Medical Research Council dyspnea scale （MMRC）,6-minute walk distance （6MWD） and BODE index were collected from 40 patients with COPD in stationary phase.Results：The CAT scores were significantly negatively correlated with FEV1 ％pred and 6MWD （r=-0.71,r=-0.85,respectively,P＜0.01）,significantly positively correlated with MMRC and BODE index（r =0.78,r =0.83,respectively,P＜0.01）,and significantly positively correlated with the SGRQ total score,the symptoms section score,the activity section score and the impacts section scores （r ranged 0.92-0.97,P＜0.01）.However,the CAT score was not correlated with BMI.Conclusions：CAT was a valid method in assessing the life quality of patients with COPD in stationary phase.