陈香露白露薄膜衣片的研制

目的:制备陈香露白露薄膜衣片,提高药物稳定性。方法:选用不同的粘合剂制备片芯,再选用不同的包衣材料进行包衣,比较陈香露白露薄膜衣片与糖衣片的稳定性。结果:采用10%聚乙烯吡咯烷酮乙醇液为粘合剂制备片芯,用隔离材料玉米阮将片芯保护,采用上海卡乐康公司的黄色或红棕色胃溶性包衣粉制备的陈香露白露薄膜衣片在外观质量上优于其它材料制备的成品,尤其是防渗油和防潮性方面优势明显;薄膜衣片稳定性优于糖衣片。结论:陈香露白露薄膜衣片质量稳定,制备工艺简单。

Preparation of Film-coated Chenxianglubailu Tablets

OBJECTIVE:To prepare film-coated Chenxianglubailu tablet and to improve its stability.METHODS:The core of the film-coated tablet was prepared with different cohesives;which were then coated with different coating substances.The stability of film-coated Chenxianglubailu tablet and that of the coated tablet were compared.RESULTS:The film-coated Chenxianglubailu tablet,with its tablet core made from10%polyvidone alcohol solution,which was protected by an insulation substance zein,which was prepared by gastric soluble yellow or marron coating power from Shanghai Colorcon Company was superior to other preparations made from other materials in appearance and quality,particularly in its oil-oozˉing-proof and moisture-proof properties.The stability of film-coated tablet was superior to that of the sugar coated tablet.CONCLUSION:The film-coated Chenxianglubailu tablet is stable in quality and its preparation is simple.