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| 正交试验法优化金银花中绿原酸的水提工艺 | |
| 引用本文： | 梅林,梅兰,李随丽. 正交试验法优化金银花中绿原酸的水提工艺[J]. 中国药业, 2007, 16(6): 42-43 |
| 作者姓名： | 梅林 梅兰 李随丽 |
| 作者单位： | 1. 重庆大学化学化工学院,重庆,400044 2. 四川省合江县中学校,四川,合江,646200 3. 重庆市急救中心,重庆,400034 |
| 摘 要： | 目的优化金银花水提最佳工艺。方法采用正交试验设计，优化水提金银花中绿原酸的工艺条件。结果水提金银花最佳条件为预浸泡8h，15倍溶剂，80℃下浸提1h，提取率为4.85％，影响因素的主次顺序为提取温度〉提取时间〉预浸泡时间〉溶剂倍数。结论该工艺条件简单、稳定、可行，绿原酸提取率可达5．57％。 |
| 关 键 词： | 金银花 绿原酸 提取 工艺 高效液相色谱法 |
| 文章编号： | 23950992 |
| 修稿时间： | 2006-09-21 |
Study on Optimal Extraction of Chlorogenic Acid from Lonicera Japonica Thumb. with water |
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| Mei Lin,Mei Lan,Li Suili. Study on Optimal Extraction of Chlorogenic Acid from Lonicera Japonica Thumb. with water[J]. China Pharmaceuticals, 2007, 16(6): 42-43 | |
| Authors: | Mei Lin Mei Lan Li Suili |
| Affiliation: | 1. College of Chemistry and Chemical Engineering, Chongqing University, Chongqing, China 400044; 2. Middle School of Hejiang County of Sichnan Province, Hefiang, Sichnan, China 646200; 3. Chongqing Emergency Medical Center, Chongqing, China 400034 |
| Abstract: | Objective To study the extracting process with water for chlorogenic acid of Lonicera Japonica Thumb. Methods Orthogonal experiment design was used to optimize the extract process of chlorogenic acid from Flos Lonicerae with water. Results The optimal conditions were：Sh of presoaking time, 15 times solvent 80℃ of extracting temperature and 1h of extracting time. 4. 85% of extract rateThe key effect of influencing factors on water extraction in turn was extracting temperature 〉 extracting time 〉 presoaking time 〉 solvent times. Conclusion The technological process is simple, steady and effective, the yield chlorogenic acid is 5. 57%. |
| Keywords: | flos lonicerae chlorogenic acid extract technological process HPLC |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |