| 半仿生提取法在中药提取中的应用 |
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| 引用本文： | 王秋红,赵珊,王鹏程,王知斌,匡海学.半仿生提取法在中药提取中的应用[J].中国实验方剂学杂志,2016,22(18):187-191. |
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| 作者姓名： | 王秋红 赵珊 王鹏程 王知斌 匡海学 |
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| 作者单位： | 黑龙江中医药大学 中药学教育部重点实验室, 哈尔滨 150040,黑龙江中医药大学 中药学教育部重点实验室, 哈尔滨 150040,黑龙江中医药大学 中药学教育部重点实验室, 哈尔滨 150040,黑龙江中医药大学 中药学教育部重点实验室, 哈尔滨 150040,黑龙江中医药大学 中药学教育部重点实验室, 哈尔滨 150040 |
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| 基金项目： | 国家重点基础研究发展计划（973计划）项目（2013CB531801） |
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| 摘 要： | 提取是中药制药工程的关键环节,直接影响着药品的质量,提取新技术的发展是中药制造工业技术升级转型的关键,关系着中药现代化的进程。作为一种新兴的提取技术,半仿生提取利用"灰思维方式",根据中药大部分药效成分未知的特点和中药物质基础整体特征,采用模拟口服给药经胃肠道吸收和转运的过程,得到有效成分更高的活性混合物。本文总结了半仿生提取技术在中药提取中的应用,并对近年来出现的新技术(微波、超声波及酶法)辅助半仿生法在中药提取中的应用进行总结,结果表明相对于传统提取技术,半仿生提取技术具有明显的优势,应用前景良好。
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| 关 键 词： | 中药 半仿生提取法 微波法 超声法 酶法 |
| 收稿时间： | 2015/7/23 0:00:00 |
Application of Semi-bionic Extraction Method for Chinese Materia Medica |
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| WANG Qiu-hong,ZHAO Shan,WANG Peng-cheng,WANG Zhi-bin and KUANG Hai-xue.Application of Semi-bionic Extraction Method for Chinese Materia Medica[J].China Journal of Experimental Traditional Medical Formulae,2016,22(18):187-191. |
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| Authors: | WANG Qiu-hong ZHAO Shan WANG Peng-cheng WANG Zhi-bin and KUANG Hai-xue |
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| Institution: | Key Laboratory of Chinese Materia Medica, Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China,Key Laboratory of Chinese Materia Medica, Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China,Key Laboratory of Chinese Materia Medica, Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China,Key Laboratory of Chinese Materia Medica, Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China and Key Laboratory of Chinese Materia Medica, Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China |
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| Abstract: | As a critical link during pharmaceutical process of traditional Chinese medicine (TCM),extraction is directly related to quality of drugs.So the key to technology transformation and upgrading of pharmaceutical equipment in Chinese materia medica enterprise is development of new extraction techniques,which concerns modernization of TCM.Based on grey mode of thinking,semi-bionic extraction mimics human gastroenteric environments to obtain extracts which contain more active compounds.This paper reviewed application of semi-bionic extraction as well as the emerging techniques (microwave,ultrasonic and enzyme) assisted semi-bionic extraction method in TCM extraction,and found remarkable advantages of semi-bionic extraction by comparing with traditional extraction method. |
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| Keywords: | traditional Chinese medicine semi-bionic extraction microwave method ultrasonic method enzymic method |
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