磁共振弥散加权成像评价肝硬化程度的初步研究

目的 探讨肝脏弥散加权成像表观弥散系数值(apparent diffusioncoefficients,ADC)评价肝硬化患者肝功能的临床应用价值.方法 对95例受检者行DWI检查,正常对照组35例,肝硬化组60例,其中Child-Pugh分级A级、B级28例,为肝硬化AB组,Child-Pugh分级C级32例,为肝硬...

Preliminary study of MR diffusion weighted imaging in evaluating the degree of liver cirrhosis

Objective： To investigate the value of MR diffusion weighted imaging （DWI） in patients with liver cirrhosis. Materials and Methods： Ninety-five cases （35 healthy volunteers and 60 patients with liver cirrhosis） were recruited with their apparent diffusion coefficients （ADC） of liver analyzed. According to liver Child-Pugh classification, 60 patients with liver cirrhosis were classified into group AB （28 cases） and group C （32 cases） with their ADC measured and compared intra-group and with that of the volunteers. Results： The ADC values of the control group, group AB and group C were （1.28±0.14）×10-3 mm2/s, （1.18±0.17）×10-3 mm2/s, and （0.91±0.34）×10-3 mm2/s, respectively. The difference was significant between group C and group AB and group C and control group （P=0.000, P=0.000）, respectively. There was no statistical significance between group AB and control group （P=0.069）. Conclusions： The value of ADC decreased as the aggravation of the hepatic cirrhosis. To some extent, the ADC value may reflect the degree of liver cirrhosis.