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Evidence based management guidelines for the detection and treatment of congenital CMV |
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| Authors: | Kadambari S Williams E J Luck S Griffiths P D Sharland M |
| Institution: | aPaediatric Infectious Diseases Unit, St George's University of London, Cranmer Terrace, London SW17 0RE, United Kingdom;bRoyal Victoria Infirmary Hospital, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, United Kingdom;cUniversity College London, Division of Infection and Immunity, Royal Free Hospital, Rowland Hill Street, London NW3 2PF, United Kingdom |
| Abstract: | CMV is the most common congenital infection in newborns worldwide. Congenital CMV causes sensorineural hearing loss in a significant proportion of infected newborns, while the majority of newborns are asymptomatic. In the last three years there have been significant advances in the diagnosis and treatment of congenital CMV. We have developed practical evidence based guidelines for the management of congenital CMV. |
| Keywords: | Abbreviations: CNS Central nervous system CMV Cytomegalovirus CrUSS Cranial Ultrasound DBS Dried blood spot FBC Full blood count IUGR Intrauterine growth restriction LFT Liver Function Test MRI Magnetic Resonance Imaging PCR Polymerase Chain Reaction SNHL Sensorineural hearing loss |
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