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Priapism in a patient with protein C deficiency
Authors:S. DARYANANI  J.T. WILDE
Abstract:Summary We present the case of a patient with classical protein C deficiency presenting with acute priapism during warfarinization for thrombophlebitis. Priapism is a well-recognized complication of a number of conditions including sickle cell disease and haematological malignancies, but to our knowledge it has not previously been reported in association with protein C deficiency. This case highlights the potential dangers of initiating oral anticoagulant therapy using conventional loading dose regimens in patients with protein C deficiency.
Keywords:Priapism  protein C deficiency  heparin  warfarin  thrombophilia
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