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造血干细胞移植治疗实体瘤研究进展
引用本文:余景星,刘心.造血干细胞移植治疗实体瘤研究进展[J].国际肿瘤学杂志,2008,35(11):823-826.
作者姓名:余景星  刘心
作者单位:西安交通大学医学院第一附属医院临床研究中心,710061
摘    要:目前实体瘤的治疗以放化疗为主,传统放化疗因存在耐药和不良反应而有一定局限性.造血干细胞移植支持下的大剂量放化疗可以减少耐药及不良反应,提高疗效,但目前仍存在移植后复发率高、生存期短的问题,如何加强后续治疗值得进一步研究.综述造血 F细胞移植治疗实体瘤的可行性、治疗时机、疗效.

关 键 词:造血干细胞移植  卵巢肿瘤  乳腺肿瘤  肾肿瘤  淋巴瘤

Progress in hematopoietic stem cell transplantation for solid tumor
YU Jing-xing,LIU Xin.Progress in hematopoietic stem cell transplantation for solid tumor[J].Journal of International Oncology,2008,35(11):823-826.
Authors:YU Jing-xing  LIU Xin
Abstract:At present,the main treatment methods of solid tumor are radiotherapy and ehemotherapy.Traditional radiotherapy and chemotherapy have certain limitations because of resistance and toxicity.High dose chemoradiotherpy with hematopoietie stem cell transplantation(HSCT)support can reduce resistance and toxicity,enhance the effectiveness of treatment.But there are still high relapse rate after transplantation and short survival period.How to strengthen the following treatment is worth of further study.This review will focus on the feasibility,treatment time,therapeutic effect and research advancement of HSCT for solid tumor.
Keywords:Hematopoietie stem cell transplantation  Ovarian neoplasms  Breast neoplasms  Kidney neoplasms  Lymphoma
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