Influence of thyroid hormones and testosterone on the activities of hepatic mitochondrial enzymes in the Indian garden lizard, Calotes versicolor |
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Authors: | O V Oommen K K Sreedeviamma |
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Institution: | Department of Zoology, University of Kerala, Trivandrum, India. |
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Abstract: | Thyroidectomy and castration in Calotes versicolor significantly decreased the activities of hepatic mitochondrial cytochrome oxidase, alpha-glycerophosphate dehydrogenase (alpha-GPDH), and succinate dehydrogenase (SDH) when compared to sham-operated controls. Administration of thyroid hormones in thyroidectomized lizards and testosterone in castrated specimens stimulated the activities of all three enzymes studied. Chloramphenicol, when injected with thyroxine prevented the hormone-stimulated activities of cytochrome oxidase and SDH, while actinomycin D and chloramphenicol, when administered along with testosterone propionate (low dose) prevented the testosterone-stimulated activities of cytochrome oxidase and alpha-GPDH. |
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