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The Meaning-Making intervention (MMi) appears to increase meaning in life in advanced ovarian cancer: a randomized controlled pilot study
Authors:Henry Melissa  Cohen S Robin  Lee Virginia  Sauthier Philippe  Provencher Diane  Drouin Pierre  Gauthier Philippe  Gotlieb Walter  Lau Susie  Drummond Nancy  Gilbert Lucy  Stanimir Gerald  Sturgeon Jeremy  Chasen Martin  Mitchell Julie  Huang Lina Nuoxin  Ferland Mira-Klode  Mayo Nancy
Affiliation:McGill University, Montreal, Quebec, Canada. henrymel@total.net
Abstract:Objective: This pilot study aimed to provide supportive evidence for the acceptability and usefulness of the Meaning‐Making intervention (MMi) in patients newly diagnosed with Stage III or IV ovarian cancer, and to provide estimates of parameters needed to design a full‐scale study. Methods: A randomized controlled trial with 24 patients (12 experimental and 12 control) was conducted. Existential well‐being (primary outcome), overall quality of life, distress, anxiety, depression and self‐efficacy were measured. Results: Compared to the control group, patients in the experimental group had a better sense of meaning in life at one and three months post‐intervention. Conclusion: The MMi seems a promising intervention for advanced cancer patients, and a full randomized controlled trial is warranted to further investigate its efficacy. Copyright © 2010 John Wiley & Sons, Ltd.
Keywords:randomized controlled trial  existential  psychosocial  intervention  advanced ovarian cancer  oncology
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