Solid variant of primary effusion lymphoma in successfully treated HIV infection: a case report |
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Authors: | Mylona E Baraboutis I G Georgiou O Rondogianni D Lekakis L J Papastamopoulos V Apostolidis I Skoutelis A T |
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Affiliation: | Fifth Department of Internal Medicine, Evaggelismos Hospital, Athens, Greece. emylon@med.uoa.gr |
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Abstract: | Primary effusion lymphoma (PEL) is a unique form of non-Hodgkin lymphoma, mainly met in severely immunocompromised, HIV-positive patients. PEL is aetiologically related to human herpes virus-8 (HHV-8) and it usually presents as a lymphomatous body cavity effusion in the absence of a solid tumour mass. Recently, cases of HIV-positive patients with HHV-8-positive solid tissue lymphomas, not associated with an effusion, have been reported (solid variant of PEL). The prognosis of PEL is reported to be poor. We report a case of an HIV-positive patient with a typical solid variant of PEL without effusion. Interestingly, his disease developed while being on stable antiretroviral therapy (ART) with high CD4 counts. He had a relatively long survival with chemotherapy and ART. |
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