微伏级T波电交替与焦虑情绪的相关性

目的:分析微伏级T波电交替(Microvolt T wave alternans,MTWA)值和患者焦虑状况的关系。方法:随机选择武汉大学人民医院2012年8月~2013年10月行平板运动试验(treadmill exercise test,TET)的患者136(男59,女77)例,年龄(53±10)岁。采用GE公司提供的Marquette MTWA分析程序,进行标准时域运动试验,记录胸前V1~V6导联的MTWA值,其中最大值以Max Valt表示,并对其进行焦虑自评量表(SAS)的问卷调查,按SAS评分将患者分为焦虑组(38例)和非焦虑组(98例),进行组间比较和相关分析。结果:在峰值心率V3导联两组MTWA值有显著差异(P0.01)。焦虑评分与峰值心率V3导联时的MTWA值呈负相关(r=-0.245,P0.01)。结论:行TET时峰值心率情况下V3导联MTWA与焦虑情绪有相关性。

Correlation between T wave alternans and anxiety

AIM：To investigate the relationship between T wave alternans and anxiety in patients so as to provide guidance for clinical judgment and intervention. METHODS： One hundred thirty-six patients （59 male and 77 female） undergoing exercise treadmill test from August 2012 to August 2013 at Renmin Hospital of Wuhan University were randomly selected for the study. Standard time domain movement exercise was conducted using Marquetee Microvolt T wave alternans （MTWA） analysis procedure provided by GE Corporation. MTWA values were recorded at V1-V6 leads and the max was recorded as MaxValt. Questionnaire of self-evaluation of anxiety scale （SAS） was performed. RESULTS： Of the 136 patients, 38 were found with anxiety and 98 without anxiety. A significant difference was found in the MTWA index at V3 when the heart rate reached the peak between patients with anxiety and patients without anxiety （P=0.001）. CONCLUSION： Results indicate that anxiety to a certain extent affects the MTWA index. Therefore, proper psychological interventional measures undertaken to alleviate patient anxiety will improve the diagnostic accuracy of MTWA, which is of significance in predicting malignant ventricular arrhythmia and sudden death.