中药血清药理学、血清药物化学的研究概况及展望

对近年来中药血清药理学、血清药物化学的研究概况进行归纳和分析,主要包括含药血清与药效的关系、含药血清的制备和血清药物化学对完善中药质量控制标准的作用。总结血清药理学、血清药物化学在体外药效研究中的优点和不足,设想中药血清指纹图谱与微透析采样技术的合理联用,推动中药血清药理学、血清药物化学的发展。

Research progress and prospects in serum pharmacology and serum pharmacochemistry of Chinese materia medica

This review generalized and analyzed the studies on serum pharmacology and serum pharmacochemistry in Chinese materia medica (CMM) in recent years, mainly including the relationship between efficacy and serum, the preparation of serum containing drugs, and the significance of serum pharmacochemistry on improvement of CMM quality control standards. We summarized the advantages and disadvantages of serum pharmacology and serum pharmacochemistry in in vitro studies on the efficacy, and further envisaged the application of serum fingerprint combined with microdialysis sampling techniques to promote the development of serum pharmacology and serum pharmacochemistry.