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桃仁的研究进展
引用本文:许筱凰,李婷,王一涛,陆金健. 桃仁的研究进展[J]. 中草药, 2015, 46(17): 2649-2655
作者姓名:许筱凰  李婷  王一涛  陆金健
作者单位:澳门大学中华医药研究院, 中药质量研究国家重点实验室, 澳门 999078;澳门大学中华医药研究院, 中药质量研究国家重点实验室, 澳门 999078;澳门大学中华医药研究院, 中药质量研究国家重点实验室, 澳门 999078;澳门大学中华医药研究院, 中药质量研究国家重点实验室, 澳门 999078
基金项目:澳门特别行政区科学技术发展基金(074/2012/A3);澳门大学研究委员会项目(MRG013/WYT/2013/ICMS,CPG2014-00012-ICMS)
摘    要:桃仁为蔷薇科植物桃或山桃的种子,具有活血祛瘀、润肠通便、止咳平喘等功效。目前对桃仁的研究仍主要集中于其活性成分苦杏仁苷的测定及其质量控制,而对其他单体成分的药理作用机制仍不明晰。综述桃仁在传统理论指导下的现代研究进展,包括其性味、炮制、配伍、质量控制,以及其化学成分和药理、毒理等方面的研究。建议对桃仁提取物中的单体成分在心血管保护、神经保护、免疫调节、抗肿瘤以及肝肾保护等药理作用机制方面进行更深入的探讨,为其资源开发和临床应用提供更详实的理论依据。

关 键 词:桃仁  苦杏仁苷  质量控制  心血管保护  神经保护  免疫调节
收稿时间:2014-11-05

Research progress in Persicae Semen
XU Xiao-huang,LI Ting,WANG Yi-tao and LU Jin-jian. Research progress in Persicae Semen[J]. Chinese Traditional and Herbal Drugs, 2015, 46(17): 2649-2655
Authors:XU Xiao-huang  LI Ting  WANG Yi-tao  LU Jin-jian
Affiliation:State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China;State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China;State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China;State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China
Abstract:The aim of this review is to summarize the advances in studies on Persicae Semen, a Chinese herbal medicine, in the fields of nature and flavor, preparation, quality control, chemical composition, pharmacology, and toxicology. Persicae Semen and its extracts present various pharmacological activities, such as cardiovascular protection, neuroprotection, immunoregulation, antitumor effects and hepatic and renal protection. Though amygdalin, one of the main components in Persicae Semen, had been well studied, the activities and mechanisms of other potential active ingredients should also be more concerned.
Keywords:Persicae Semen  amygdalin  quality control  cardiovascular protection  neuroprotection  immunoregulation
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