| 丙型肝炎核心抗原与丙型肝炎抗体联合检测在丙型肝炎诊疗中的作用 |
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| 引用本文： | 李会平. 丙型肝炎核心抗原与丙型肝炎抗体联合检测在丙型肝炎诊疗中的作用[J]. 检验医学与临床, 2011, 0(13): 1575-1575,1577. DOI: 10.3969/j.issn.1672-9455.2011.13.019 |
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| 作者姓名： | 李会平 |
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| 作者单位： | 河北省邢台市人民医院检验二科,054001 |
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| 摘 要： | 目的了解丙型肝炎核心抗原(HCV-cAg)检测在丙型肝炎(简称丙肝)诊疗中的作用。方法采用酶联免疫吸附试验(ELISA)对400例健康体检者和600例邢台市人民医院住院患者进行HCV-cAg和丙肝抗体(抗-HCV)联合检测,HCV-cAg阳性标本用PCR荧光定量法检测HCV-RNA确认。结果 400例健康体检者6例(1.5%)抗-HCV阳性,0例HCV-cAg阳性;600例住院患者12例(2%)抗-HCV阳性,4例(0.67%)HCV-cAg阳性(含1例抗-HCV阳性),HCV-RNA确认3例,二者符合率为75%。结论 HCV-cAg较抗-HCV的检测将丙肝病毒感染的"窗口期"提前了,是HCV的早期诊断指标,HCV-cAg与抗-HCV联合检测有助于提高HCV的诊断率,对于HCV筛查有重要意义,是有效防范丙肝传播的重要手段,值得推广。
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| 关 键 词： | 丙型肝炎病毒 丙肝核心抗原 丙肝抗体 联合检测 |
Effect of joint detection on core antigen of hepatitis C and hepatitis C antibody in clinical diagnosis of HCV |
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| LI Hui-ping. Effect of joint detection on core antigen of hepatitis C and hepatitis C antibody in clinical diagnosis of HCV[J]. Laboratory Medicine and Clinic, 2011, 0(13): 1575-1575,1577. DOI: 10.3969/j.issn.1672-9455.2011.13.019 |
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| Authors: | LI Hui-ping |
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| Affiliation: | LI Hui-ping(Second Department of Clinical Laboratory,Xingtai People′s Hospital,Hebei 054001,China) |
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| Abstract: | Objective To evaluate the effect of detection on hepatitis C core antigen(HCV-cAg) in clinical diagnosis of hepatitis C virus(HCV).Methods We detected the level of HCV-cAg and hepatitis C antibody(HCV-Ab) in 400 health person and 600 in-patients from our hospital by ELISA method.The HCV-cAg positive specimens were confirmed by detecting HCV-RNA by PCR method.Results 6(1.5%) positive cases of HCV-Ab in 400 healthy person,12(2%) positive cases of HCV-Ab and 4(0.67%) positive cases of HCV-cAg in 600 in-patient... |
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| Keywords: | hepatitis C virus hepatitis C core antigen hepatitis C antibody joint detection |
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