Overview of oral antithrombotic treatment in elderly patients with atrial fibrillation |
| |
| Affiliation: | 1. Klinik für Innere Medizin III – Kardiologie, Angiologie, Internistische Intensivmedizin;2. Statistical Consultant, Ingelheim am Rhein, Rhineland-Palatinate, Germany;3. Medicine CardioMetabolism & Respiratory, Boehringer Ingelheim International GmbH, Binger Strasse 173, Ingelheim am Rhein, Rhineland-Palatinate, Germany;4. Medizinische Fakultät Mannheim, Universitätsklinikum Mannheim, Theodor-Kutzer Ufer 1-3, Mannheim, Baden-Württemberg, Germany;5. Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada;6. Sidney Kimmel Medical College at Jefferson University, Philadelphia, Pennsylvania; Lankenau Institute for Medical Research and The Heart Center, Wynnewood, Pennsylvania;7. Uppsala Clinical Research Center and Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden |
| |
| Abstract: | Atrial fibrillation (AF) is an age-related arrhythmia, particularly affecting elderly patients. The ultimate goals in the treatment of AF are to improve prognosis and quality of life. Anticoagulants are effective for stroke prevention in AF patients, however, managing anticoagulation in elderly patients is especially challenging; requiring a comprehensive assessment of the patient and deep understanding of available therapies and doses to maximize the net benefit. This review summarizes available evidence on the efficacy and safety of anticoagulation therapy, and provides contemporary updates on the management of elderly patients with AF. |
| |
| Keywords: | Atrial fibrillation Anticoagulation Elderly Bleeding Stroke |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
